WHAT IS SKIN MICROBIOME?

 

   

Skin microbiome refers to the trillions of bacteria, virus, fungi, and mites that live on human skin. The “Human Microbiome Project” research, which ran from 2007 to 2016, uncovered a large diversity of microbiome living in harmony with human skin cells and the role they play in health and disease. These organisms feed on dead skin, turn sebum into natural moisturiser, and most importantly, protect the skin from potential assault by foreign organisms to toxic substances.

The delicate balance found within these microbes are crucial to skin health; when this balance is interrupted, sensitive skin conditions such as eczema, rosacea, and acne may occur. Unsurprisingly, our modern urban lifestyles and habits have affected the skin microbiome balance. Here are some examples of how this balance has been interrupted. 

  • Harsh cleansing 
  • Excessive use of hand sanitiser and antiseptic hand wash 
  • Unhealthy diet 
  • Stress 
  • Pollution 
  • UV rays
  • Using skincare or makeup products that are not skin microbiome friendly

Because every ingredient that touches the skin can impact the delicate microbiome balance, we created a microbiome-friendly skincare line that incorporates carefully selected and tested ingredients. This ensures that our finished products supports the skin microbiome diversity. Our skincare line aims to restore the delicate balance of your skin microbiome and enhance your skin health. The final result is calmer and more radiant skin.

Our skin microbiome-friendly range contains: 

  • Prebiotics – ingredients that feed bacteria e.g. alpha/beta glucans, fructose, inuline and maltodextrin.
  • Postbiotics – are fractions and by-products of bacteria which enhances the  skin microbiome e.g. lactic acid, bacteria lysate, fermented actives
  • Phytonutrients  – to nourish and improve over all skin health and hydration.

ALL our functional ingredients are tested to be skin microbiome-friendly.

100% free from petrol-chemically derived ingredients

100% biodegradable

Benefits of the Skin Microbiome Series include: 

  • Skin Repair 
  • Skin Protection 
  • Increased Moisturization 
  • Skin Radiance 
  • Anti-Ageing
  • Calm and Soothed Skin

Our Innovation Journey 

Our innovation started with collaboration with researchers from the Agency for Science,Technology and Research’s (A*STAR) Institute of Materials Research and Engineering (IMRE). Here, scientists carried out bacteria viability studies to determine how each ingredient affects the certain species of skin microbiota. The IMRE team also used machine learning to help optimise the performance of our formulations.

Research in the skin microbiome field is still ongoing but many studies have established the link between sensitive skin and the lack of the skin microbiome diversity. Our mission is to design and create skin microbiome friendly products that are able to enhance and balance the skin microbiome diversity. The human skin’s microbiome is diverse, and keeping its balance is crucial to enhancing skin health. Bearing in mind that each ingredient could drastically impact the skin microbiome balance, we selected every ingredients meticulously. We rigorously run bacterial viability testing to help in the selection process. The ingredients selected must meet two criteria:

1.friendly to skin microbiome 

2.low/no impact to the environment


In addition, we have collaborated with MyMicrobiome in Germany, who has developed the world’s first standard for microbiome-friendly products. Our microbiome series have been tested and certified by MyMicrobiometo be microbiome-friendly.

Another important collaboration is with scientists from Sequential Skin, who have innovated a patented skin patch test specially designed to collect a comprehensive sample of skin cells and bacteria cells, to assess one’s genetics and microbiome accurately.

These collaborations are pivotal is our innovation process. After about 18 months of research and development, we have launched Asia’s first certified microbiome skincare and the world’s first customizable microbiome skincare line.


In-House Focus Group Clinical Trials 

An exploratory in-vivo study was carried out in 10 volunteers of all skin types (male and female 17 to 50 years of age). These participants used the Sage and Ylang Skin Microbiome Friendly series - which consist of the Gentle Face Cleanser, Beauty Essence, and Soothing Moisturiser - twice a day for a period of one month.

Before they started using this range, a skin analysis using OBSERV 520 and microbiome sampling using Sequential Skin Kit were carried out. Skin patch strip was taken from the forehead of our participants first thing in the morning before washing their faces.

During the next one month, participant used our microbiome series 2 times a day. At the end of the month, participants carried out another skin analysis using OBSERV 520 and microbiome sampling using Sequential Skin Kit.

 

Here is a list of the documented results observed by the participants: 

  • Increased comfort of the skin 
  • Increased skin hydration 
  • Increased overall radiance 
  • Decreased dryness 
  • Soothed sensitive skin 
  • Lessened skin redness and oiliness

Here is the summary of the results from OBSERV 520 and Sequential Skin Test:

  • increase in skin microbiome diversity in almost 99% of participant
  • increase in the number of good bacteria in 100% of participants: Lactobacillus Acidophilus and Staphylococcus Epidermidis
  • reduction in the number of bad bacteria in 100% of participants: Staphylococcus Aureus which is associated with skin condition like eczema.
  • sebum production greatly reduced in 100% of participants with oily skin types. 

 

 

References

1 Segre, Julie A, et al. “Skin Microbiome in Health and Disease.” Genome Biology, BioMed Central, 11 Oct. 2010, genomebiology.biomedcentral.com/articles/10.1186/gb-2010-11-s1-i18. 

2 Trivedi, Bijal. “Microbiome: The Surface Brigade.” Nature News, Nature Publishing Group, 19 Dec. 2012, www.nature.com/articles/492S60a. 

3 Barren-Hill, Florence. The Skin Microbiome; Importance & Formation, pastiche-training.com/online-courses/specialist-subjects/the-skin-microbiome-importance-and-formation/.

4 Dreno, Brigitte, et al. “Skin Microbiome and Acne Vulgaris: Staphylococcus, a New Actor in Acne.” Experimental Dermatology, U.S. National Library of Medicine, 10 Apr. 2017, pubmed.ncbi.nlm.nih.gov/28094874/. 

5 Prescott, Susan. Skin Microbiome and Its Role in Skin Barrier Dysfunction and Atopic Dermatitis, Research Review Publication, 2018, researchreview.co.nz. 

6 Khmaladze, Ia, and Susanne Fabre. “Dead or Alive? A New Dilemma of Probiotic Skin Care for Healthier Skin.” Journal of Gynecology and Women's Health, Juniper Publishers, 10 Dec. 2019, juniperpublishers.com/jojdc/JOJDC.MS.ID.555580.php. 

7 Muizzuddin, Neelam, et al. “Physiological Effect of a Probiotic on Skin.” Journal of Cosmetic Science, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/23286870/. 

 

 

 

 

NEW CUSTOMER? SIGN UP