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WHAT IS SKIN MICROBIOME?

 

"Skin Microbiome" refers to the billions of bacteria, virus, fungi, and mites that live on human skin. The 2013 “Human Microbiome Project” research uncovered a large diversity of microbiome living in harmony with human skin cells. These organisms feed on dead skin, turn sebum into natural moisturiser, and most importantly, protect the skin from potential assault by foreign organisms to toxic substances.

The delicate balance found within these microbes are crucial to skin health; when this balance is interrupted, skin conditions such as eczema, rosacea, and acne may occur. Unsurprisingly, our modern urban lifestyles and habits have affected the skin microbiome balance. Here are some examples of how this balance has been interrupted. 

  • Harsh cleansing 
  • Excessive use of hand sanitiser and antiseptic hand wash 
  • Unhealthy diet 
  • Stress 
  • Pollution 
  • UV rays
  • Using skincare products that are not skin microbiome friendly

Because every ingredient that touches the skin can impact the delicate microbiome balance, we created a microbiome-friendly skincare line that incorporates carefully selected and tested ingredients. This ensures that our finished products promote the microbiome balance and diversity of the skin. We aim to restore the delicate balance of your skin microbiome, enhance your skin health, and make your skin calmer and more radiant.

Our skin microbiome-friendly range contains: 

  • Pre-biotics – which feed and promote the growth of good bacteria 
  • Post-biotics – which enhances the biodiversity of the skin, strengthens skin fermentation, and soothes and freshens skin 
  • Plant Actives – which improve skin health and hydration 

ALL our functional ingredients are tested to be skin microbiome-friendly.

Benefits of the Skin Microbiome Friendly products include: 

  • Skin Repair 
  • Skin Protection 
  • Increased Moisturization 
  • Skin Radiance 
  • Anti-Ageing
  • Calm and Soothed Skin
Our R & D Journey 

We wanted to create the world’s first customizable and certified microbiome-friendly skincare line that is backed by science, but were aware that this would require support from a scientific research institution. We have a passion for the science behind a microbiome-related skincare range. Because of the skin microbiome’s diverse nature and its crucial role in balancing and enhancing skin health, as well as bearing in mind how each ingredient can impact the skin microbiome, we select our ingredients thoroughly and carefully.

As we developed formulations for a new microbiome-friendly skincare range, researchers from the Agency for Science, Technology and Research’s (A*STAR) Institute of Materials Research and Engineering (IMRE) did bacteria viability studies for us. The IMRE team also used machine learning to help us optimise the performance of our formulations.

We discovered the science behind microbiome-related skincare and developed a range of clean beauty customizable microbiome-friendly skincare. The human skin’s microbiome is diverse, and keeping its balance is crucial to enhancing skin health. Bearing in mind that each ingredient could drastically impact the skin, ingredients in the skincare range were selected carefully. Various ingredients were shortlisted and specially selected to ensure that the skincare products would be friendly to the skin microbiome.

In addition, we have collaborated with MyMicrobiome in Germany, who has developed the world’s first standards for microbiome-friendly products. Some of our products have been tested and certified by MyMicrobiome to be microbiome-friendly. We also worked with Sequential Skin where they have developed the world’s first at-home skin test, that deeply analyses the skin genetics and skin microbiome.

We have innovated, created and validated the first of its kind customizable and certified microbiome-friendly skincare in the World. Our development capabilities in skincare is backed by scientific studies done with MyMicrobiome and Sequential Skin.

In-House Focus Group Clinical Trials 

A clinical trial was conducted on 15 participants over a period of one month. These participants used the Sage and Ylang Skin Microbiome Friendly series - which consist of the Gentle Face Cleanser, Beauty Essence, and Soothing Moisturiser - twice a day for a month. Before they started using this range, a skin analysis using OBSERV 520 and skin patch test using Sequential Test Kit were done. These tests were repeated after one month.

Here is a list of the documented results observed by the participants: 

  • Increased comfort of the skin 
  • Increased skin hydration 
  • Increased overall radiance 
  • Decreased dryness 
  • Soothed sensitive skin 
  • Lessened skin redness and oiliness

Here is the summary of the results from OBSERV 520 and Sequential Skin test:

  • increase in skin microbiome diversity in almost 99% of participant
  • increase in the amount of good bacteria in 100% of participants: Lactobacillus Acidophilus and Staphylococcus Epidermidis
  • reduction in the amount of bad bacteria in 100% of participants: Staphylococcus Aureus which is associated with skin condition like eczema.
  • sebum production greatly reduced 

 

References

[1]https://www.dsm.com/markets/personal-care/en_US/trends/the-skin-microbiome.html

 

 

[2]Barren-Hill, Florence. The Skin Microbiome; Importance & Formation, pastiche-training.com/online-courses/specialist-subjects/the-skin-microbiome-importance-and-formation/.

[3]https://www.ncbi.nlm.nih.gov/books/NBK279255/

 

 

[4]http://advances.sciencemag.org/content/4/2/eaao4502

 

 

[5]http://www.idph.state.il.us/envhealth/pcmites.htm

 

 

[6]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425451/

 

 

[7]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535073/

 

 

[8]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535073/

 

 

[9]https://www.nature.com/articles/s41598-017-18181-5

 

 

[10]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425451/figure/F1/

 

 

[11]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425451/

 

 

[12]https://www.nature.com/articles/s41522-017-0022-5

 

 

[13]https://www.dsm.com/markets/personal-care/en_US/trends/the-skin-microbiome.html

 

 

[14]https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1004436

 

 

[15]https://www.nature.com/articles/s41598-017-18181-5

 

 

[16]https://www.ncbi.nlm.nih.gov/pubmed/30632097

 

 

[17] https://www.mayoclinic.org/diseases-conditions/acne/symptoms-causes/syc-20368047

 

 

[18]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535073/

 

 

[20]https://www.mayoclinic.org/diseases-conditions/atopic-dermatitis-eczema/symptoms-causes/syc-20353273

 

 

 

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